| MERCEDES-BENZ S-CLASS (W221) S 250 CDI (221.003, 221.103) | 2143 | 204 | Дизель | 2011-2013 |
| MERCEDES-BENZ S-CLASS (W221) S 280 (221.054) | 2996 | 231 | Бензин | 2006-2013 |
| MERCEDES-BENZ S-CLASS (W221) S 300 (221.054, 221.154) | 2996 | 231 | Бензин | 2006-2013 |
| MERCEDES-BENZ S-CLASS (W221) S 320 CDI (221.022, 221.122) | 2987 | 235 | Дизель | 2005-2009 |
| MERCEDES-BENZ S-CLASS (W221) S 320 CDI 4-matic (221.080, 221.180) | 2987 | 211 | Дизель | 2005-2013 |
| MERCEDES-BENZ S-CLASS (W221) S 320 CDI 4-matic (221.080, 221.180) | 2987 | 235 | Дизель | 2006-2013 |
| MERCEDES-BENZ S-CLASS (W221) S 350 (221.056, 221.156) | 3498 | 272 | Бензин | 2005-2013 |
| MERCEDES-BENZ S-CLASS (W221) S 350 4-matic (221.087, 221.187) | 3498 | 272 | Бензин | 2008-2013 |
| MERCEDES-BENZ S-CLASS (W221) S 350 BlueTec (221.026, 221.126) | 2987 | 258 | Дизель | 2011-2013 |
| MERCEDES-BENZ S-CLASS (W221) S 350 BlueTEC 4-matic (221.083, 221.183) | 2987 | 258 | Дизель | 2011-2013 |
| MERCEDES-BENZ S-CLASS (W221) S 350 CGI (221.057, 221.157) | 3498 | 306 | Бензин | 2011-2013 |
| MERCEDES-BENZ S-CLASS (W221) S 350 CGI 4-matic (221.082, 221.182) | 3498 | 306 | Бензин | 2011-2013 |
| MERCEDES-BENZ S-CLASS (W221) S 400 Hybrid (221.095, 221.195) | 3498 | 279 | Гибрид | 2009-2013 |
| MERCEDES-BENZ S-CLASS (W221) S 420 CDI (221.028, 221.128) | 3996 | 320 | Дизель | 2006-2009 |
| MERCEDES-BENZ S-CLASS (W221) S 450 (221.070, 221.170) | 4663 | 340 | Бензин | 2005-2013 |
| MERCEDES-BENZ S-CLASS (W221) S 450 4-matic (221.084, 221.184) | 4663 | 340 | Бензин | 2005-2013 |
| MERCEDES-BENZ S-CLASS (W221) S 450 CDI (221.028, 221.128) | 3996 | 320 | Дизель | 2009-2013 |
| MERCEDES-BENZ S-CLASS (W221) S 500 (221.071, 221.171) | 5461 | 388 | Бензин | 2005-2013 |
| MERCEDES-BENZ S-CLASS (W221) S 500 4-matic (221.086, 221.186) | 5461 | 388 | Бензин | 2005-2013 |
| MERCEDES-BENZ S-CLASS (W221) S 500 CGI (221.073, 221.173) | 4663 | 435 | Бензин | 2011-2013 |
| MERCEDES-BENZ S-CLASS (W221) S 500 CGI 4-matic (221.094, 221.194) | 4663 | 435 | Бензин | 2011-2013 |
| MERCEDES-BENZ S-CLASS (W221) S 600 (221.176) | 5513 | 517 | Бензин | 2005-2013 |
| MERCEDES-BENZ S-CLASS (W221) S 63 AMG (221.074, 221.174) | 5461 | 544 | Бензин | 2011-2013 |
| MERCEDES-BENZ S-CLASS (W221) S 63 AMG (221.074, 221.174) | 5461 | 571 | Бензин | 2012-2013 |
| MERCEDES-BENZ S-CLASS (W221) S 63 AMG (221.077, 221.177) | 6208 | 525 | Бензин | 2006-2013 |
| MERCEDES-BENZ S-CLASS (W221) S 65 AMG (221.179) | 5980 | 612 | Бензин | 2005-2013 |
| MERCEDES-BENZ S-CLASS (W221) S 65 AMG (221.179) | 5980 | 630 | Бензин | 2010-2013 |